Tumor. Chemotherapy most used for the adjuvant treatment of breast cancer was the CMF is a combination of:. cyclophosphamide (Cytoxan), methotrexate and 5-flurourac More recently the AC therapy (combination of Adriamycin and Cytoxan Taxol is another drug Brain Plus IQ that can be used in breast cancer treatment. If your cancer is diagnosed as "ER positive" or "ER negative." "RE" mean estrogen receptor. This is a receiver, or a "docking site" to which estrogen can bind. If a tumor has these receptors (ER positive cancer), this means that the natural hormones your body may have an effect on cancer growth. .