The NuPhedrine website claims that clinical trials were performed to measure its safety and effectiveness. Weight reduction isn't about not eating for one day or missing two sequential foods every day but to observe some rules and tips. With thousands of weight loss programs out there Wii's weight loss program sets it aside from the low carbohydrate diets of the Atkins diet and even the over-the-counter pills like Alli. Your goal is to exercise at least 60 minutes a day.