Natures Choice Keto Warfarin works by inhibiting the synthesis of active forms of vitamin K- dependent coagulation factors in the liver (II, VII, IX, X). It occurs in the form of two isomers: S-warfarin and R-warfarin. The first one works 5 times stronger.Warfarin is rapidly and completely absorbed and is 98-99% bound to plasma proteins. About 90% of the oral dose is excreted in the urine, mainly as metabolites.After stopping treatment with warfarin, the concentration of prothrombin (i.e. the coagulation factor in the blood plasma ) returns to its previous level only after about 4-5 days.Warfarin was not used immediately in medicine, it was initially used as ... rat poison. It wasn't until 1954 that warfarin was approved for human treatment after testing. Natures Choice Keto

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